This is the generic detection for a family of advanced adware that have evolved from the old PUP.Multiplug family. They are known for trying different tactics to stop security software from being downloaded and installed on infected systems. For example, a variant of this adware may use a proxy that keeps the system from visiting sites where such software can be downloaded.
Once installed, Malwarebytes can remove this adware without further user interaction. Visit our blog or our forums to learn about methods that will allow you to install Malwarebytes on an affected system.