PUP.Optional.Wajam is the detection name for Wajam, a browser add-on marketed as a “social search.”
PUP.Optional.AuslogicsBoostSpeed is a “system optimizer” and one of the products marketed by Auslogics. These system optimizers promise to speed up your computer. They use utilities to do this that are available for free and sometimes even built into Windows. They also promise to clean up invalid registry entries to achieve this, a method that Microsoft explicitly advises against.
This type of PUP is usually installed by the users themselves as a result of heavy advertising.
You can use the built-in uninstaller, but Malwarebytes completely removes this threat. No further cleanup is required.