Trojan.Agent refers to a generic Trojan malware detection. It is used for detections that are either associated with no specific malware families or not enough information is available to pinpoint the malware family.
Trojan.ShadowBrokers is the generic detection for tools that exploit SMB vulnerabilities that were released by the so-called ShadowBrokers aka Equation group.
Malwarebytes protects users from Trojan.ShadowBrokers by using real-time protection.
Malwarebytes can detect and remove Trojan.ShadowBrokers without further user interaction.