This is a generic detection for the Brontok Worm. The Brontok worm has been around since 2005 in one form or another. Most variants have the ability to disable security software and participate in DDOS attacks.
Worm.Qakbot is a detection for a family of worms that can spread through network shares and removable drives. It gathers information about the affected system and also installs a backdoor, mostly to be used by banking Trojans.
Worm.Qakbot is usually installed by exploit kits.
Malwarebytes can remove Worm.Qakbot without further user interaction. It is recommended, however, to perform a full system scan to check for the presence of the backdoor and the banking Trojan. It is also recommended to change all passwords that could have been stolen from the affected system.